1) If you are logging in for the first time after turning your machine on, you may find that the game crashes (get that red box symbol at the top of the screen). When you quit and relog in, it works fine.
2) In a quest which has objectives such as extinguish x number of flames or pull x levers or whatever, if you are interrupted while doing the objectives, they will autocomplete and appear to be done, but your counter for them won't update - so the quest then can't be completed. Happened to me in stromvauld mine - trés annoying as its so easy to miss the corpses anyway. After combing the dungeon twice over for bodies I'd missed, thankfully the game crashed on me LOL. I found out afterwards it was a bug :p The general advice for this at the moment is make sure everything that could interrupt you is dead before attempting the quest objective - and don't move either thus interrupting yourself and bugging it out :p